Secure your reservation on our site
Up to 10% less
than Booking.com
Check rooms and rates
From149US$ /night
Check-in
22Nov2025Select date
Check-out
23Nov2025Select date
Rooms and Guests2 Guests, 1 Room
Key details

Hotel overview and key features

4521 W.41St Street, Sioux Falls, South Dakota, United States, 57106

La Quinta By Wyndham Sioux Falls is a 3-star hotel located 9.5 miles from Sioux Falls Regional Airport, offering a complimentary airport shuttle. The property is situated in an area with good shopping, near landmarks like the Empire Mall and the Denny Sanford PREMIER Center. Guests can explore downtown Sioux Falls, including the SculptureWalk and historic Queen Bee Mill Ruins.

Comfortable Guest Rooms

All guestrooms at La Quinta Inn & Suites by Wyndham Sioux Falls include air conditioning, free WiFi, and flat-screen HDTVs. Each non-smoking room features a mini-refrigerator, microwave, coffee maker, and ironing amenities. The 8.8/10-rated hotel ensures comfort with its well-equipped accommodations.

Dining & Refreshments

Guests start their mornings with a free Bright Side Breakfast(R), featuring waffles, scrambled eggs, and biscuits and gravy. The hotel also offers a manager's reception Monday through Thursday evenings. Complimentary coffee is available in all rooms.

Local Attractions

The Great Plains Zoo & Delbridge Museum of Natural History and Wild Water West Waterpark are nearby for family-friendly outings. Guests can visit Falls Park or explore the Butterfly House & Aquarium in Sertoma Park. The hotel's proximity to the Empire Mall provides additional leisure options.

Business & Facilities

La Quinta Inn & Suites Sioux Falls features a 990-square-foot meeting room accommodating up to 60 guests. The state-of-the-art business center includes two workstations and a printer. A fitness center and indoor pool are available for guest use.

View all

Choose your ideal room style

Choose from family rooms, suites, flexible cancellation & more
Queen Room Two Queen Beds City View Non-Smoking
2 persons
28 m² 
Heating
Air conditioning
King Room City View Non-Smoking
2 persons
28 m² 
Heating
Air conditioning
Deluxe Queen Suite City View Non-Smoking
2 persons
28 m² 
Heating
Air conditioning
Deluxe Queen Suite City View Mobility Access or Non-Smoking
2 persons
28 m² 
Heating
Air conditioning
Click button to see more rooms
Show all rooms
Show all roomsLess

Prices and Availability

Check availability and prices for your travel dates right now!

Getting around

Transportation options available

City Centre
Sioux Falls 4.8 km
Airports
Sioux Falls Regional (FSD) 13.8 km
Stronsay (soy) 94.0 km

Facilities

Stay relaxed and refreshed just minutes from the airport

General

  • Non-smoking rooms
  • Free Wi-Fi
  • Free parking
  • 24-hour reception
  • Pets allowed

Sports & Fitness

  • Fitness centre

Services

  • Free airport shuttle
  • Laundry
  • Shops/Commercial services

Business

  • Business centre
  • Meeting/ Banquet facilities

Spa & Leisure

  • Indoor swimming pool

Room features

  • Air conditioning
  • Heating
  • Tea and coffee facilities

Bathroom

  • Free toiletries

Media

  • AM/FM alarm clock
Show more

Location info

4521 W.41St Street, Sioux Falls, South Dakota, United States, 57106
Map view
4521 W.41St Street, Sioux Falls, South Dakota, United States, 57106
Nearby
Casino
Black Diamond Casino
480 m
Restaurants
Fazoli's
690 m
4224 West Empire Place
Taco John's
840 m
4001 W 41st St
McDonald's
670 m
4000 W 41st St
Culver's
930 m
4001 W 41st St
Arby's
730 m
3820 W 41st St
B & G Milkyway
890 m
5508 W 41st St
Burger King
1.7 km
4900 West Empire Place
Fuji Sushi Express
1.7 km
5000 W Empire Mall
Looking for early discounts?
Get airport hotel deals before everyone else
Check Rates

Next best alternative

Consider them for your next trip.
Check-in
22Nov2025Select date
Check-out
23Nov2025Select date
Rooms and Guests2 Guests, 1 Room